Phosphonocephem compound

Details Phosphonocephem compound Phosphonocephem compound

C - Chemistry, Metallurgy

07

F

C07F 9/6561 (2006.01) A61K 31/675 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2418614

A cephem compound (particularly its crystal) represented by the formula [I], wherein X is CH3COOH, CH3CH2COOH or CH3CN, and n is 0 to 5, is useful as an antibacterial agent (particularly anti-MRSA agent) and shows superior quality such as high solid stability, possible long-term stable preservation and the like.

La présente invention concerne un composé de phosphonocéphème correspondant à la formule (I) dans laquelle : X représente CH3COOH, CH3CH2COOH ou CH3CN et n représente 0 à 5. Le composé céphème (notamment, sous forme de cristaux) est utile en tant qu'agent antibactérien (en particulier en tant qu'agent contre le Staphylococcus aureus résistant à la méthicilline),est présente l'avantage de posséder une stabilité de solide améliorée, et peut être stocké de manière stable pour une longue période, et analogues.

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