Phosphonomethoxymethylpurine/pyrimidine derivatives

C - Chemistry – Metallurgy – 07 – F

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C07F 9/6561 (2006.01) A61K 31/675 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 239/47 (2006.01) C07D 239/54 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 473/40 (2006.01) C07F 9/6512 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 2297294

Compounds of the following formulas which have anti-tumor and anti-viral activity and are especially useful in treating viral infections, their compositions and use. A phosphonomethoxymethyoxymethyl purine/pyrimidine derivative of the formula (see formula I) wherein X and X' are the same or different and are hydrogen or alkyl. R and R' are the same or different and are hydrogen, alkyl, hydroxyalkyl or R"CO-where R" is an alkyl and B is a purine or pyrimidine base.

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