Phosphonooxymethyl esters of taxane derivatives

Details Phosphonooxymethyl esters of taxane derivatives Phosphonooxymethyl esters of taxane derivatives

C - Chemistry, Metallurgy

07

F

C07F 9/547 (2006.01) A61K 31/665 (2006.01) A61K 31/695 (2006.01) C07D 305/14 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01) H01L 21/48 (2006.01)

Patent

CA 2129288

The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives which are water soluble phosphonooxymethyl ethers, and the pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions thereof, and their use as antitumor agents.

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