Phosphopeptide enrichment of compositions by fractionation...

Details Phosphopeptide enrichment of compositions by fractionation... Phosphopeptide enrichment of compositions by fractionation...

C - Chemistry, Metallurgy

07

K

C07K 1/22 (2006.01) B01J 43/00 (2006.01) G01N 1/34 (2006.01)

Patent

CA 2743499

Phosphorylated peptides are extracted from digests of biological liquids and other peptide mixtures by fractiona-tion on ceramic hydroxyapatite. The ceramic hydroxyapatite is readily usable in a centrifuge, allowing for rapid fractionations of a large number of small volume samples, and accordingly high throughput.

Linvention consiste à extraire des peptides phosphorylés de digestions de liquides biologiques et autres mélanges de peptides par fractionnement sur hydroxyapatite céramique. Lhydroxyapatite céramique est aisément utilisable dans une centrifugeuse, permettant des fractionnements rapides d'un grand nombre déchantillons de faible volume et donc un rendement élevé.

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