Phosphoramidates useful as antitumor agents

Details Phosphoramidates useful as antitumor agents Phosphoramidates useful as antitumor agents

C - Chemistry, Metallurgy

07

F

C07F 9/547 (2006.01) A61K 31/66 (2006.01) C07F 9/572 (2006.01) C07F 9/6506 (2006.01) C07F 9/655 (2006.01) C07F 9/6553 (2006.01)

Patent

CA 2161548

Cyclophosphanamide analogs are provided of general formula (II), wherein R1 and R2 are each (C2-C6)alkyl, substituted with a leaving group such as halo Image (II) or alkylsulphonyl, R3 and R4 are the same as R1 and R2 or are H and Ar is a heteroaromatic ring and the pharmaceutically salts thereof.

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