Phosphoric diester

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6558 (2006.01) A61K 8/67 (2006.01) A61K 31/665 (2006.01) C07F 9/655 (2006.01)

Patent

CA 2186654

This invention provides a phosphoric diester of formula (?) which is available on di-esterification of phosphoric acid with L-ascorbic acid involving its 5- hydroxyl group and tocopherol involving its hydroxyl group or a pharmacologically acceptable salt thereof. Image (I) The compound of the invention can be used with advantage as an antioxidant (radical-scavenging) agent and a prophylactic and therapeutic agent for ischemic organ disorders (e.g. myocardial infarction, heart failure, arrhythmia, cerebral infarction, stroke (cerebral apoplexy), renal failure, etc.).

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