C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/6558 (2006.01) A61K 8/67 (2006.01) A61K 31/665 (2006.01) C07F 9/655 (2006.01)
Patent
CA 2186654
This invention provides a phosphoric diester of formula (?) which is available on di-esterification of phosphoric acid with L-ascorbic acid involving its 5- hydroxyl group and tocopherol involving its hydroxyl group or a pharmacologically acceptable salt thereof. Image (I) The compound of the invention can be used with advantage as an antioxidant (radical-scavenging) agent and a prophylactic and therapeutic agent for ischemic organ disorders (e.g. myocardial infarction, heart failure, arrhythmia, cerebral infarction, stroke (cerebral apoplexy), renal failure, etc.).
Iemura Masahito
Nakamura Masayuki
Ogata Kazumi
Saito Noriko
Sakaue Takahiro
Kirby Eades Gale Baker
Senju Pharmaceutical Co. Ltd.
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