Phosphorous containing compounds including...

Details Phosphorous containing compounds including... Phosphorous containing compounds including...

C - Chemistry, Metallurgy

07

F

C07F 9/40 (2006.01) A61K 31/66 (2006.01) A61P 35/00 (2006.01) C07F 9/42 (2006.01) C07F 9/547 (2006.01) C07F 9/6518 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 2651395

Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. Particularly disclosed are phosphonate esters. Compounds, methods of making the compounds, medicaments and method of manufacture of medicaments and therapeutic methods with applications against cancer including breast cancer, melanoma, colon cancer, leukemia and lymphoma, and other cancer cells are described.

L'invention concerne des composés et des méthodes associées de synthèse ainsi que l'utilisation de composés et de polythérapies dans le traitement du cancer et la modulation de l'apoptose dans des cellules. Cette invention concerne en particulier des esters de phosphonate. Ladite invention concerne en outre des composés, des procédés de production desdits composés, des médicaments et des procédés de production desdits médicaments ainsi que des méthodes thérapeutiques contre le cancer, y compris le cancer du sein, le mélanome, le cancer du colon, la leucémie et le lymphome, ainsi que d'autres cellules cancéreuses.

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