Phosphorus-containing compounds & uses thereof

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6561 (2006.01) A61K 31/436 (2006.01) A61K 31/66 (2006.01) A61K 31/662 (2006.01) A61K 45/06 (2006.01) A61L 31/16 (2006.01) C07D 498/18 (2006.01)

Patent

CA 2472341

This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is -O-, -S- or -NR2-; Q is absent or (if A is -O-, -S- or -NR2-) Q may be -V-, -OV-, -SV-, or -NR2V-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR2VA; J = (I) - or - (II), K is O or S; each occurrence of Y is independently -O-, -S-, -NR2-, or chemical bond linking a R5 moiety to P; and the other variables are as defined herein.

L'invention concerne une nouvelle famille de composés contenant du phosphore et comportant une fraction JQA- dans laquelle: A est absent ou signifie -O-, -S- ou NR?2¿-; Q est absent ou (si A signifie -O-, -S- ou NR?2¿-) Q peut être -V-, -OV-, -SV- ou - NR?2¿V-, V étant une fraction aliphatique, hétéroaliphatique, aryle ou hétéroaryle, de telle sorte que J est lié au noyau cyclohexyl directement, par A ou par VA, OVA, SVA ou - NR?2¿VA; J = (I) - ou - (II) ; K est O ou S; chaque occurrence de Y étant indépendamment -O-, -S-, - NR?2¿- ou une liaison chimique reliant une fraction R?5¿ à P; les autres variables étant comme définies dans l'invention.

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