Phosphorus-containing dendrimers as transfection agents

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6581 (2006.01) C07F 9/24 (2006.01) C07F 9/6593 (2006.01) C08G 83/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2392697

The invention concerns phosphorus-containing dendrimers and their uses, as gene transfection agents, in vitro and in vivo, including in the treatment of human and animal diseases. Said agents or vectors are in particular suited for delivering to appropriate target cells, nucleic acid sequences of interest.

Dendrimères phosphorés et leurs applications, comme agents de transfection de gènes, in vitro et in vivo, y compris dans le traitement des maladies humaines et animales. Lesdits agents ou vecteurs sont notamment aptes à dispenser à des cellules cibles convenables, des séquences d'acide nucléique d'intérêt.

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