Phosphorus-containing hmg-coa reductase inhibitors

Details Phosphorus-containing hmg-coa reductase inhibitors Phosphorus-containing hmg-coa reductase inhibitors

C - Chemistry, Metallurgy

07

F

C07F 9/6512 (2006.01) A61K 31/675 (2006.01) C07D 239/26 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07F 7/22 (2006.01) C07F 9/42 (2006.01)

Patent

CA 2072394

HX42 ABSTRACT PHOSPHORUS-CONTAINING HMG-CoA REDUCTASE INHIBITORS Novel phosphorus-containing compounds which inhibit the activity of HMG-CoA reductase, including a 5-pyrimidinyl-containing moiety. Pharmaceutical compositions and methods of use for the treatment or prevention of hypercholesterolemia, athero- schlerosis, hyperlipoproteinaemia and hyperlipi- demia are provided.

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