Phosphorylated glycosidase inhibitor prodrugs

Details Phosphorylated glycosidase inhibitor prodrugs Phosphorylated glycosidase inhibitor prodrugs

C - Chemistry, Metallurgy

12

P

167/228, 260/291

C12P 17/12 (2006.01) A61K 31/44 (2006.01) C07F 9/59 (2006.01)

Patent

CA 2023404

A method is provided for converting therapeutic glycosidase inhibitors to novel prodrugs by phosphorylation of a free hydroxyl group on the molecule to substantially reduce the glycosidase inhibitory activity without thereby substantially reducing the therapeutic activity.

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