Photochemical nucleic acid-labeling reagent having a...

Details Photochemical nucleic acid-labeling reagent having a... Photochemical nucleic acid-labeling reagent having a...

C - Chemistry, Metallurgy

12

Q

195/1.12, 150/8.

C12Q 1/68 (2006.01) G01N 33/532 (2006.01)

Patent

CA 1293939

ABSTRACT OF THE DISCLOSURE A photochemical nucleic acid-labeling reagent of the formula Image wherein Q is a photoreactive residue of a nucleic acid-binding ligand; L is a detectable label residue; R is hydrogen, C1 to C7-alkyl, aryl, hydroxy, or C1 to C7-alkoxy; x is an integer from 2 through 7; and y is an integer from 3 through 10; wherein R and x, respectively, can be the same or different each time they appear in the formula. The reagent is useful in the highly efficient labeling of nucleic acids for the purpose of detection in hybridization assays.

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