Photochemotherapeutic method using precursors of...

A - Human Necessities – 61 – K

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A61K 31/197 (2006.01) A61K 31/195 (2006.01) A61K 41/00 (2006.01) A61N 5/06 (2006.01)

Patent

CA 2461070

Medicaments for detecting and treating malignant and non-malignant tissue abnormalities and lesions of the skin; conjunctiva; respiratory, digestive and vaginal mucosa; endometrium and urothelium; and for ablating the endometrial tissue and treating body fluids containing suspended abnormal cells, and for treating cancers of the nervous system are prepared from 5-aminolevulinic acid or precursor therof and subsequently administered to the patient in an amount sufficient to induce syntheses fluorescence and/or photosensitizing concentrations or protoporphyrin IX in the abnormal cells, followed by exposure of the abnormal cells to light of photoactivating wavelengths.

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