Photodynamic therapy for the treatment of hyperactive...

A - Human Necessities – 61 – K

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A61K 41/00 (2006.01) A61K 31/409 (2006.01) A61K 31/555 (2006.01) A61N 5/06 (2006.01) A61P 17/00 (2006.01) A61P 17/10 (2006.01)

Patent

CA 2568744

The present method involves the photodynamic treatment of hyperactive gland disorders. The method involves the topical administration of a photosensitizer composition comprising hydrophobic and/or lipophilic green porphyrins such as lemuteporfin, polyethylene glycol and skin penetration enhancers such as oleyl alcohol and TRANSCUTOLTM to affected skin and subsequent exposure of that skin to energy of a wavelength capable of activating the photosensitizer.

LE présent procédé met en jeu le traitement photodynamique d'affections de glandes hyperactives. Le procédé met en jeu l'administration locale d'une composition photosensibilisatrice comprenant des porphyrines vertes hydrophobes et/ou lipophiles telles que la lémutéporfine, le polyéthylène glycol et des agents d'amélioration de la pénétration dans le peau tels que l'alcool d'oléyl et le TRANSCUTOLTM sur la peau affectée, ainsi que l'exposition ultérieure de cette peau à une énergie à une certaine longueur d'onde pouvant activer l'agent photosensibilisateur.

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