A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/409 (2006.01) A61K 41/00 (2006.01) A61K 49/00 (2006.01) A61P 17/00 (2006.01) A61P 29/00 (2006.01) C07D 487/22 (2006.01)
Patent
CA 2490326
Various diagnostics with the application of photodynamic diagnosis/therapy (photodynamic therapy: PDT) wherein use is made of highly selective uptake of an iminochlorinaspartic acid derivative or its pharmacologically acceptable salt in neovessels and selective uptake thereof in cancer cells. More specifically, remedies for rheumatism, remedies for inflammatory keratosis, agents for confirming the location of a sentinel lymph node and diagnostics for cancer metastasis which contain as the active ingredient an iminochlorinaspartic acid derivative represented by the following formula (I) or its pharmacologically acceptable salt: (I) wherein Asp represents aspartate.
L'invention concerne divers diagnostics comportant l'application de diagnostic/thérapie photodynamique (thérapie photodynamique: TPD) qui fait appel à une absorption hautement sélective d'un dérivé d'acide iminochlorinaspartique ou de son sel pharmacologiquement acceptable dans des néovaisseaux et à son absorption sélective dans des cellules cancéreuses. Plus précisément, l'invention concerne des remèdes contre les rhumatismes, des remèdes contre la kératose inflammatoire, des agents pour confirmer l'emplacement d'un ganglion lymphatique sentinelle et des diagnostics de métastases cancéreuses qui contiennent comme agent actif un dérivé d'acide iminochlorinaspartique représenté par la formule suivante (I) ou son sel pharmacologiquement acceptable, dans laquelle Asp représente l'aspartate.
Nakae Yoshinori
Nakajima Susumu
Sakata Isao
Hamamatsu Photonics K.k.
Smart & Biggar
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