Photodynamic therapy with spatially resolved dual...

A - Human Necessities – 61 – B

Patent

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A61B 5/00 (2006.01) A61B 18/22 (2006.01)

Patent

CA 2576264

An instrument for photodynamic therapy applies treatment light from a dye laser, white light, and ultraviolet fluorescence excitation light from an LED onto a lesion and surrounding areas in a time-multiplexed manner. The reflected white light is analyzed in a spectrometer to determine a correction for the dynamic optical spectral properties of the patient's tissue. Light emitted by fluorescence from the lesion and the surrounding areas is analyzed in another spectrometer, and the results are corrected in a computer, using the correction. An optical switch has been developed for the instrument, using a bistable solenoid and a sled.

L'invention concerne un instrument de thérapie photodynamique permettant d'appliquer une lumière de traitement provenant d'un laser à colorants, une lumière blanche et une lumière d'excitation fluorescente ultraviolette provenant d'une LED sur une lésion et sur les zones environnantes en mode multiplexage dans le temps. La lumière blanche réfléchie est analysée dans un spectromètre afin de déterminer une correction des propriétés spectrales optiques dynamiques du tissu d'un patient. La lumière émise par fluorescence provenant de la lésion et des zones environnantes est analysée dans un autre spectromètre, et les résultats sont corrigés dans un ordinateur à l'aide de la correction. On a développé un commutateur optique pour cet instrument qui utilise un solénoïde bistable et un chariot.

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