Photopheresis treatment of leukocytes

Details Photopheresis treatment of leukocytes Photopheresis treatment of leukocytes

A - Human Necessities

61

K

A61K 41/00 (2006.01) A61K 31/35 (2006.01) A61K 31/37 (2006.01) A61M 1/36 (2006.01)

Patent

CA 2250919

A method of treating infections of mononuclear blood cells, other than retroviral infections, is disclosed. A method of modulating the function of monocytes is also disclosed. The method involves the treatment of a patient's blood with a photoactivatable compound followed by ultraviolet light activation of the photoactivatable compound. The blood treated as such is returned to the patient in a process known as extracorporeal photopheresis. Monocyte function is modulated by this treatment.

On décrit un procédé permettant de traiter les infections de globules mononucléaires, ces infections ne comprenant par les infections rétrovirales, ainsi qu'un procédé permettant de moduler la fonction des monocytes. Le procédé consiste à traiter le sang d'un patient avec un composé photo-activable puis à activer ledit composé photo-activable avec de la lumière ultraviolette. Le sang traité de cette manière est réintroduit dans le patient selon une procédure appelée photophérèse extracorporelle. La fonction monocytaire est modulée par ce traitement.

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