Photoreactive ru (ii) complexes anchored on...

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 23/00 (2006.01) A61K 31/7135 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2679344

The present invention is related to photoreactive Ru (II) complexes anchored on a G- containing oligonucleotide, e.g. compound 1, the method for obtaining them and their use, especially for targeting specific nucleotide sequences that become photocrosslinked to the photoreactive Ru (II) complex anchored to the G- containing oligonucleotide.

La présente invention concerne des complexes de Ru (II) photoréactifs ancrés sur un oligonucléotide contenant du G, le procédé d'obtention de ceux-ci et leur utilisation, notamment pour cibler des séquences de nucléotides spécifiques qui se sont réticulées au complexe de Ru (II) photoréactif ancré à l'oligonucléotide contenant du G.

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