A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 41/00 (2006.01) A61K 31/409 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2347045
The methods of the invention can be used to treat mycobacterial infections, or any disease or disorder that is caused by (or aggravated by) an intracellular pathogen. Accordingly, the invention features methods for treating a subject who has a disorder that is associated with an intracellular pathogen by administering, to a subject, a molecular conjugate that includes a photosensitizer (a term used herein to refer to a light activatable compound) and a targeting moiety, the targeting moiety being capable of targeting the conjugate to the intracellular pathogen.
Les méthodes de l'invention peuvent être utilisées pour traiter des infections mycobactériennes ou n'importe quelle maladie ou trouble provoqués (ou aggravés) par un agent pathogène intracellulaire. Par conséquent, l'invention présente des méthodes de traitement d'un sujet présentant un trouble associé à un agent pathogène intracellulaire par administration audit sujet d'un conjugué moléculaire contenant un photosensibilisant (un terme utilisé ici pour faire référence à un composé photoactivable) et une fraction ciblante, la fraction ciblante étant capable de cibler le conjugué sur l'agent pathogène intracellulaire.
Gross Jerome
Hasan Tayyaba
Nau Gerard J.
Smart & Biggar
The General Hospital Corporation
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