Photostabilisation of molsidomine

Details Photostabilisation of molsidomine Photostabilisation of molsidomine

C - Chemistry, Metallurgy

07

D

260/246.5

C07D 413/04 (2006.01) A61K 31/535 (2006.01) A61K 47/10 (2006.01) A61K 47/22 (2006.01)

Patent

CA 1232275

ABSTRACT OF THE DISCLOSURE Photostabilised formulation of molsidomine, a photostabil- iser and, if appropriate, further auxiliaries and additives, characterised in that the photostabiliser is a compound of the general formula I Image (I) wherein Y denotes a hydroxyl group, alkoxy having 1 or 2 C atoms or .beta.-hydroxyethoxy and Z denotes a group of the formula Image or Y and Z together denote a structural element of the formula II or III Image (II) Image (III) in which the free oxygen valency is attached in the Y-position and the free carbon valency is attached in the Z-position, the compounds of formula I are surprising effective as photostabili- zers for molsidomine and provide improved protection during its preparation, transport, storage and further processing.

470804

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