Phthalane derivatives, compositions thereof and a method of...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/87 (2006.01)

Patent

CA 1094087

PHTHALANE DERIVATIVES, COMPOSITIONS THEREOF AND A METHOD OF PREPARATION THEREOF Abstract of the Disclosure The present invention relates to phthalanes of the following general formula: Image I wherein R1 and R2 each represents halogen, a trifluoro- methyl group, a cyano group or R-CO- wherein R is an alkyl- LUND-32 CANADA radical with from 1-4 C-atoms inclusive, as well as acid addition salts thereof with pharmaceutically acceptable acids. It is an object of the present invention to provide phthal- anes of Formula I, a method of making the same, a method for the alleviation, palliation, mitigation, or inhibition of the mani- festations of certain physiological-psychological abnormalities of animals therewith, and pharmaceutical compositions comprising such compounds as active ingredient. Other objects will be apparent to one skilled in the art and still other objects will become apparent hereinafter.

269610

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