Phthalazine derivatives as parp inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/04 (2006.01) A61K 31/502 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2569824

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, L1, L2, X, Y, Q and Z have defined meanings.

Cette invention concerne des composés représentés par la formule (I), leur utilisation comme inhibiteurs de PARP, ainsi que des compositions pharmaceutiques comprenant ces composés de formule (I), dans laquelle R1, R2, L1, L2, X, Y, Q et Z ont les notations définies dans les pièces descriptives de la demande.

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