Phthalazinone derivatives and their use as medicament to...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/10 (2006.01) A61K 31/502 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 25/16 (2006.01) A61P 29/00 (2006.01) C07D 403/14 (2006.01) C07D 407/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2683682

A compound of the formula (I): wherein: A and B together represent an optionally substituted, fused aromatic ring; X is selected from H and F; R1 and R2 are independently selected from H and methyl; RN1 is selected from H and optionally substituted C1-7 alkyl; RN2 is selected from H, optionally substituted C1-7 alkyl, C3-7 heterocyclyl and C5-6 aryl; or RN1 and RN2 and the nitrogen atom to which they are bound form an optionally substituted nitrogen containing C5-7 heterocyclic group.

L'invention concerne un composé selon la formule (I) : dans laquelle : A et B représentent ensemble un cycle aromatique condensé éventuellement substitué ; X est choisi parmi H et F ; R1et R2 sont indépendamment choisis parmi H et méthyle ; RN1 est choisi parmi H et C1-7 alkyle éventuellement substitué ; RN2 est choisi parmi H, C1-7 alkyle éventuellement substitué, C3-7 hétérocyclyle et C5-6 aryle ; ou RN1 et RN2 et l'atome de nitrogène auquel ils sont liés forment un groupe hétérocyclique C5-7 éventuellement substitué contenant de l'azote.

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