C - Chemistry – Metallurgy – 09 – B
Patent
C - Chemistry, Metallurgy
09
B
C09B 47/08 (2006.01) A61K 31/695 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01) C09B 47/04 (2006.01)
Patent
CA 2086942
2086942 9201753 PCTABS00010 The present invention relates to a series of novel phthalocyanine compositions (or compounds) suitable for use as photosensitizers for photodynamic therapy. Specifically, the invention relates to a series of new aluminum (Al) and/or silicon (Si) phthalocyanines having substituted amine or quaternary ammonium axial ligands attached to the central metal, and the use of these new phthalocyanine compositions for the treatment of cancer through photosensitization. Moreover, the present invention is directed to the methods of preparing these compositions for use in photodynamic therapy. The phthalocyanine compounds have formula (I), wherein M = AlOSi(CH3)2(CH2)3N(CH3)2; AlOSi(CH3)2(CH2)3N(CH3)3+I-; HOSiOSi(CH3)2(CH2)3N(CH3)2, or HOSiOSi(CH3)2(CH2)3N(CH3)3+I-.
Kenney Malcolm E.
Oleinick Nancy L.
Rihter Boris D.
Kenney Malcolm E.
Oleinick Nancy L.
Rihter Boris D.
Sim & Mcburney
University Hospitals Of Cleveland
LandOfFree
Phthalocyanine photosensitizers for photodynamic therapy and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phthalocyanine photosensitizers for photodynamic therapy and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phthalocyanine photosensitizers for photodynamic therapy and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1750095