Phycoerythrin labeled thyronine analogues and assays using...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/72 (2006.01) C07C 235/32 (2006.01) G01N 33/533 (2006.01) G01N 33/543 (2006.01) G01N 33/553 (2006.01) G01N 33/58 (2006.01) G01N 33/78 (2006.01)

Patent

CA 2440664

The invention provides fluorescent analogues of thyroid hormones T3 and T4. Also provided are assays for thyroid hormones utilizing the compounds of the invention. The assays of the invention are in both one-step and two-step formats and allow the determination of both T3 and T4 concentration in a sample.

Cette invention concerne des analogues fluorescents des hormones thyroïdiennes T¿3? et T¿4?. Elle concerne également des dosages pour les hormones thyroïdiennes qui mettent en oeuvre les composés de l'invention. Les dosages de l'invention se présentent dans un format réalisable en une étape ou en deux étapes, et permettent de déterminer la teneur tant de T¿3? que de T¿4? dans un échantillon.

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