Physically modified beclomethasone dipropionate suitable for...

Details Physically modified beclomethasone dipropionate suitable for... Physically modified beclomethasone dipropionate suitable for...

C - Chemistry, Metallurgy

07

J

167/197

C07J 5/00 (2006.01) A61K 9/72 (2006.01) A61K 31/57 (2006.01)

Patent

CA 1253806

ABSTRACT PHYSICALLY MODIFIED BECLOMETHASONE DIPROPIONATE SUITABLE FOR USE IN AEROSOLS A method for preparing a stable aerosol formulation of beclomethasone dipropionate in which the steroid is contacted with an alcohol containing 1 to 5 carbon atoms to form a crystalline solvate therewith, the crystalline material so formed being reduced to a particle size below 10 microns and thereafter dispersed in a composition comprising chlorofluorocarbon propellents.

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