Physiologically active protein originating in mammals

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2282557

A novel physiologically active protein molecule originating in mammals which is expressed specifically in arteriosclerosis and/or coronary restenosis and is likely to relate closely to the onset and progress of these diseases; a DNA encoding this protein molecule; an antibody reactive with the molecule; and medicinal compositions containing the above protein molecule and antibody. The above protein molecule, DNA and antibody are useful in treating and preventing arteriosclerosis.

L'invention concerne une nouvelle molécule de protéine physiologiquement active provenant de mammifères, laquelle est exprimée spécifiquement dans l'artériosclérose et/ou la resténose coronaire et est susceptible d'être en étroite relation avec le début et la progression de ces maladies; un ADN codant cette molécule protéique; un anticorps réagissant avec la molécule et des compositions médicinales contenant la molécule protéique et l'anticorps précité. La molécule protéique, l'ADN et l'anticorps précité sont utiles dans le traitement et la prévention de l'artériosclérose.

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