Physiologically active substance p-23924, its production and...

C - Chemistry – Metallurgy – 12 – P

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260/396, 195/122

C12P 7/66 (2006.01) C07C 46/00 (2006.01) C07C 50/32 (2006.01) C12P 13/04 (2006.01)

Patent

CA 1206111

ABSTRACT OF THE DISCLOSURE The compound of the formula: Image wherein R1 is hydrogen, methyl or hydroxymethyl, R2 is hydrogen or methoxy, R3 is hydroxy or methoxy, and R4 is hydrogen or a group Image is novel, and the compound is of use as inhibitors of animal tissue fibrosis, or biochemical reagents. The compound of the above formula wherein R4 is a group Image may be produced by cultivating a microorganism belonging to the genus Streptomyces and capable of producing the compound, and the compound of the formula wherein R4 is hydrogen may be produced by replacing the Image group with a hydrogen atom by reduction.

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