Pi-3 kinase inhibitor prodrugs

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 311/22 (2006.01) A61K 31/5377 (2006.01) A61P 25/00 (2006.01) C07D 407/12 (2006.01) C07D 475/04 (2006.01)

Patent

CA 2518916

The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.

L'invention concerne de nouveaux promédicaments d'inhibiteurs de PI-3 kinase. Les nouveaux composés sont LY294002 et leurs analogues comprenant un amine quaternarisé de manière réversible.

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