Pi3 kinases

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 513/04 (2006.01) A61K 31/428 (2006.01) A61K 31/429 (2006.01) A61P 35/00 (2006.01) C07D 277/84 (2006.01)

Patent

CA 2579279

The invention relates to the novel compounds of formula (1), which, due to their pharmaceutical effect as PI3 kinase modulators, are suitable for use in the therapy and treatment of inflammatory or allergic diseases. Examples of these diseases are inflammatory and allergic respiratory diseases, inflammatory diseases of the gastro-intestinal system and of the locomotor apparatus, inflammatory and allergic skin diseases, inflammatory ophthalmic diseases, diseases of the nasal mucosa, inflammatory or allergic autoimmune reactive conditions, or renal inflammations.

L'invention concerne de nouveaux composés représentés par la formule (I), pouvant être employés de façon thérapeutique dans le traitement de maladies inflammatoires ou allergiques en raison de leur activité pharmaceutique de modulateurs de PI3-kinases. Lesdites composés permettent notamment de traiter des maladies inflammatoires et allergiques des voies respiratoires, des maladies inflammatoires du tractus gastro-intestinal et de l'appareil locomoteur, des maladies dermiques inflammatoires et allergiques, des maladies oculaires inflammatoires et allergiques, des maladies de la muqueuse nasale, des états pathologiques inflammatoires et allergiques faisant intervenir des réactions auto-immunitaires ou des inflammations des reins.

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