Picornavirus l proteinase and methods of making and using...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/57 (2006.01) C07K 7/08 (2006.01) C07K 14/09 (2006.01) C07K 14/095 (2006.01) C07K 14/47 (2006.01) C12N 9/50 (2006.01) C12P 21/06 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2195669

Methods of making and using Picornavirus (foot-and-mouth disease virus) L proteinase peptides (PLPPs) are provided, including, but not limited to, expression of DNA encoding all or a portion thereof, such as a Picornavirus L proteinase (PLP) and variants thereof, as well as methods for determining active sites and inhibitors of a PLP.

L'invention concerne des procédés pour la fabrication et l'utilisation de peptides de Picornavirus-L-protéinase et notamment, mais pas exclusivement, l'expression d'ADN codant pour tout ou partie de ceux-ci, comme une Picornavirus-L-protéinase (PLP) et ses variantes, ainsi que des procédés pour déterminer des sites actifs et des inhibiteurs d'une PLP.

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