Piezoelectric nerve guidance channels

Details Piezoelectric nerve guidance channels Piezoelectric nerve guidance channels

A - Human Necessities

61

B

326/1, 128/120

A61B 17/04 (2006.01) A61B 17/11 (2006.01) A61L 31/04 (2006.01) A61L 31/14 (2006.01) C08F 14/18 (2006.01) A61B 17/00 (2006.01) A61F 2/00 (2006.01)

Patent

CA 1331208

Abstract of the Disclosure Medical devices and methods employing piezoelectric materials, such as polyvinylidene fluoride (PVDF) and other biocompatible piezoelectric polymers, are disclosed for use as guidance channels in regenerating nerves. The devices can be formed by a tubular piezoelectric membrane adapted to receive the ends of a severed or damaged nerve. The tubular conduit defines a lumen through which axons can regenerate to restore motor and/or sensory functions. The piezoelectric materials generate transient electrical charges upon mechanical deformation which augment the ability of axons to bridge the gap between the proximal and distal nerve stumps.

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