Pigr-1, a member of immunoglobulin gene superfamily

Details Pigr-1, a member of immunoglobulin gene superfamily Pigr-1, a member of immunoglobulin gene superfamily

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2240631

PIGR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-1 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), among others and diagnostic assays for such conditions.

Polypeptides PIGR-1, polynucléotides et méthodes pour l'obtention de ces polypeptides par des techniques recombinantes. On divulgue également des méthodes pour utiliser les polypeptides PIGR-1 et les polynucléotides pour la conception de méthodes destinées au traitement de la polyarthrite rhumatoïde, de la sclérose en plaques, du psoriasis, du lupus érythémateux disséminé, de la maladie intestinale inflammatoire, etc.; essais diagnostiques pour ces affections.

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