Pigr-2, a member of immunoglobulin gene superfamily

Details Pigr-2, a member of immunoglobulin gene superfamily Pigr-2, a member of immunoglobulin gene superfamily

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2241392

PIGR-2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-2 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), Multiple Sclerosis (MS), psoriasis, Systemic Lupus Erythematosus (SLE) and Inflammatory Bowel Disease (IBD), among others and diagnostic assays for such conditions.

Divulgation de polypeptides et de polynucléotides PIGR-2, ainsi que de méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes d'utilisation des polypeptides et des polynucléotides PIGR-2 dans la conception de protocoles pour le traitement de la polyarthrite rhumatoïde (RA), de la sclérose en plaques (MS), du psoriasis, du lupus érythameux aigu disséminé (SLE) et de la maladie inflammatoire intestinale (IBD), entre autres, de même que des épreuves diagnostiques pour ces conditions sont également dévoilées.

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