Piperazine and piperidine derivatives

Details Piperazine and piperidine derivatives Piperazine and piperidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) C07D 205/04 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 277/06 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2398822

The present invention relates to piperazine and piperidine derivatives of Formula (1), with Q, X, Y, A, B and P as defined herein, which are especially useful for treating or preventing neuronal damage, particularly damage associated with neurological diseases. These compounds are also useful for stimulating nerve growth. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage or for stimulating nerve growth.

La présente invention concerne des dérivés de pipérazine et de pipéridine particulièrement utiles dans le traitement ou dans la prévention de lésions neuronales, en particulier de lésions associées aux affections neurologiques. Ces composés sont également utiles pour stimuler la croissance du tissu nerveux. Cette invention concerne également des compositions renfermant ces composés et des méthodes d'utilisation de ces compositions pour le traitement et la prévention de lésions neuronales ou pour stimuler la croissance du tissu nerveux.

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