Piperazine compound capable of inhibiting prostaglandin d...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 1/04 (2006.01) A61P 3/04 (2006.01) A61P 7/04 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 15/00 (2006.01) A61P 15/06 (2006.01) A61P 15/08 (2006.01) A61P 17/00 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 17/10 (2006.01) A61P 19/02 (2006.01) A61P 21/00 (2006.01) A61P 21/04 (2006.01) A61P 25/00 (2006.01) A61P 25/20 (2006.01) A61P 25/28 (2006.01) A61P 27/14 (2006.01) A61P 27/16 (2006.01) A61P 29/

Patent

CA 2754613

Disclosed is a piperazine compound represented by general formula (I) or a salt thereof. [In the formula, R1 repre-sents an alkyl group having 1 to 6 carbon atoms; R2 represents any one selected from a hydroxy group, an alkyl group having 1 to 6 carbon atoms which may have a substituent, a group -(C=O)-N(R3)(R4) and a group -(C=O)-OR5; R3 and R4 may be the same as or different from each other, and R3 and R4 independently represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms which may have a substituent, or R3, R4 and a nitrogen atom to which R3 and R4 are bound may together form a saturated heterocyclic group; R5 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms which may have a substituent; and n represents 1 or 2.]

Composé de pipérazine représenté par la formule générale (I) ou un sel de ce composé. [Dans cette formule, R1 représente un groupe alkyle ayant 1 à six atomes de carbone; R2 représente un quelconque groupe pris parmi un groupe hydroxy, un groupe alkyle ayant 1 à 6 atomes de carbone pouvant avoir un substituant, un groupe -(C=O)-N(R3)(R4) et un groupe -(C=O)-OR5; R3 et R4 peuvent être identiques ou différents, et R3 et R4 représentent indépendamment un atome d'hydrogène ou un groupe alkyle ayant 1 à 6 atomes de carbone pouvant avoir un substituant, ou bien R3, R4 et un atome d'azote auquel R3 et R4 sont liés peuvent former un groupe hétérocyclique saturé; R5 représente un atome d'hydrogène ou un groupe alkyle ayant 1 à 6 atomes de carbone et pouvant avoir un substituant; et n vaut 1 ou 2.

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