Piperazine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/20 (2006.01) A61K 31/495 (2006.01) A61P 3/04 (2006.01) C07D 241/04 (2006.01) C07D 295/205 (2006.01) C07D 295/21 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2430601

The present invention refers to chemical compounds of formula (I) as well as pharmaceutically usable salts, solvates and esters thereof, wherein R1 to 44, A1, A2 m and n have the significance given in claim 1. They can be used in the form of pharmaceutically preparations for the treatment or prevention of disorders of the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes, obesity and sleep apnoea.

La présente invention concerne des composés chimiques de formule (1) ainsi que des sels, des solvates et des esters utilisables sur le plan pharmaceutique desdits composés, la signification de R?1¿ à R?4¿, A?1¿, A?2¿, m et n étant donnée dans la revendication 1. Lesdits composés peuvent être utilisés sous forme de préparations pharmaceutiques pour le traitement ou la prévention des troubles du système nerveux central, des troubles cardio-vasculaires, des troubles gastro-intestinaux, des diabètes, de l'obésité et de l'apnée du sommeil.

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