Piperazine derivatives and methods of use

Details Piperazine derivatives and methods of use Piperazine derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 409/14 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2499732

The invention provides 2-carboxamide piperazine compounds of formula I, R3 . I N\ ' N ~' R2I(0)z- o R4 I wherein R', R2, R3 and R4 are as defined in the claims and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.

Cette invention concerne des composés pipérazine 2-carboxamide représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans les revendications. Cette invention concerne également des procédés de traitement et des compositions pharmaceutiques qui utilisent ou comprennent un ou plusieurs de ces composés. Les composés de cette invention servent à traiter l'infécondité chez les mammifères.

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