Piperazine derivatives as 5ht1a antagonists

Details Piperazine derivatives as 5ht1a antagonists Piperazine derivatives as 5ht1a antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2191871

Compounds are disclosed which have general formula A, where R a and R b are each hydrogen or methyl and R c is hydrogen, halo or C1-4 alkyl optionally in the form of a pharmaceutically acceptable acid addition salt. The compounds are useful in the treatment of CNS disorders.

On décrit des dérivés de formule générale A, où R<a> et R<b> représentent chacun hydrogène ou méthyle et R<c> hydrogène, halo ou C1-4 alkyle, dérivés prenant éventuellement la forme d'un sel d'addition d'acide pharmacologiquement acceptable. Ces composés s'utilisent dans le traitement des troubles du système nerveux central.

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