C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61P 11/06 (2006.01) C07D 295/02 (2006.01) C07D 295/084 (2006.01) C07D 295/135 (2006.01) C07D 307/22 (2006.01) C07D 333/24 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2467966
The present invention relates to piperazine derivatives of Formula (I), wherein: R1-R4, A, L, and X are as defined in the specification. The compounds are useful as CCR-3 receptor antagonists, and therefore, may be used for the treatment of CCR-3 mediated diseases such as asthma.
L'invention concerne de dérivés pipérazinés de formule (I), dans laquelle R?1¿ R?4¿, A, L, et X sont tels que définis dans le descriptif. Les composés sont utiles comme antagonistes du récepteur CCR-3 et peuvent servir, par conséquent, dans le traitement de maladies induites par CCR-3.
Du Bois Daisy Joe
Kertesz Denis John
Sjogren Eric Brian
Smith David Bernard
Wang Beihan
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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