C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/04 (2006.01) A61K 31/381 (2006.01) A61K 31/4015 (2006.01) A61K 31/4439 (2006.01) C07D 207/24 (2006.01) C07D 295/02 (2006.01) C07D 333/08 (2006.01) C07D 333/10 (2006.01)
Patent
CA 2575359
The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Re, Rf and Y are as defined in the specification. The compounds are partial or full agonists at the growth hormone secretagogue (GHS) receptors . Pharmaceutical compositions comprising the compounds, methods of preparing the compounds, uses of the compounds and methods involving the compounds are also provided.
Cette invention concerne des composés représentés par la formule (I) ou des sels de ces composés pharmaceutiquement acceptables. Dans cette formule, Ra, Rb, Rc, Rd, Re, Rf et Y sont comme définis dans le descriptif. Ces composés sont des agonistes partiels ou complets des récepteurs du sécrétagogue de l'hormone de croissance (GHS). L'invention concerne également des compositions contenant ces composés, des méthodes de fabrication desdits composés, leur utilisation et leurs modalités d'utilisation.
Dean David Kenneth
Gaiba Alessandra
King Nigel Paul
Takle Andrew Kenneth
Witherington Jason
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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