Piperazine methanimine derivatives, process for their...

Details Piperazine methanimine derivatives, process for their... Piperazine methanimine derivatives, process for their...

C - Chemistry, Metallurgy

07

D

260/267.1

C07D 241/04 (2006.01) C07C 43/225 (2006.01) C07D 295/03 (2006.01) C07D 295/092 (2006.01) C07D 295/195 (2006.01)

Patent

CA 1127156

NEW PIPERAZINE METHANIMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF. ABSTRACT OF THE DISCLOSURE. The invention relates to compounds having the formula : Image (I) in which : - the substituents R1, R2 and R3 represent independently from each other a hydrogen atom, a halogen atom, a trifluoro- methyl radical, a saturated or unsaturated straight- or branched-chain C1-6 alkyl radical, a C1-6 alkoxy radical the alkyl moiety of which may be saturated or unsaturated and straight- or branched-chained, a benzyloxy radical or a hydroxy radical; - the substituents R5, R6 and R7 represent independently from each other a hydrogen atom, a halogen atom, a trifluoro- methyl radical, a straight- or branched-chain saturated or unsaturated C1-6 alkyl radical, a C1-6 alkoxy radical the alkyl moiety of which may be saturated or unsaturated and straight- or branched-chained, or a hydroxy radical; - the substituent R4 represents a hydrogen atom, a C1-6 alkyl radical or a hydroxy radical, - m and n represent independently a number equal to 0, 1 or 2, - X represents an oxygen atom, a sulfur atom or a single bond, and their pharmaceutically acceptable acid addition salts. These compounds are therapeutically useful for the control of the cardiovascular system.

324866

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