Piperazine-piperidine antagonists and agonists of the 5-ht1a...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61P 43/00 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2611711

The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agon f its. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction.

La présente invention concerne de nouveaux composés pipérazino-pipéridiniques. Ils conviennent comme agents se liant à 5-HT1A, et particulièrement comme antagonistes et agonistes du récepteur 5-HT1A. Ces composés conviennent pour le traitement de troubles du système nerveux central tels que les troubles de la cognition, les troubles à anxiété, la dépression et les dysfonctions sexuelles.

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