Piperazines useful for treating pain

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/74 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61P 1/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2551862

Compounds of formulae (I) and (II) where Ar1, Ar2, R3, R4, and m, are disclosed herein, or a pharmaceutically acceptable salt thereof (a "Nitro(cyano)vinylpiperazine Compound"); compositions comprising an effective amount of a Nitro(cyano)vinylpiperazine Compound; and methods for treating or preventing pain and other conditions in an animal comprising administering to an animal in need thereof an effective amount of a Nitro(cyano)vinylpiperazine Compound are disclosed.

La présente invention a trait à des composés de formule (I) et (II), dans laquelle : Ar¿1?, Ar¿2?, R¿3?, R¿4?, et m sont tels que définis dans la description, ou un sel de ceux-ci pharmaceutiquement acceptable (un composé nitro(cyano)vinylpipérazine) ; à des compositions comportant une quantité efficace d'un composé nitro(cyano)vinylpipérazine ; et à des procédés pour le traitement ou la prévention de la douleur et d'autres conditions chez un animal comprenant l'administration à un animal qui en a besoin d'une quantité efficace d'un composé nitro(cyano)vinylpipérazine.

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