Piperazinophenyl-and piperazinophenyloxycarboxylic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/155 (2006.01) A61K 31/495 (2006.01) C07D 213/74 (2006.01) C07D 213/81 (2006.01)

Patent

CA 2225091

Compounds having fibrinogen receptor-antagonistic activity, of the general formula I Image in which Z is oxygen or a methylene group, B is a phenyl or pyridyl radical, R1 is hydrogen or a group forming a biolabile ester, and their physiologically acceptable acid addition salts and physiologically acceptable salts of acids of formula I.

Composés possédant une activité d'antagoniste des récepteurs du fibrinogène, de formule générale I Image , où Z est un oxygène ou un groupe méthylène, B est un groupe phényle ou pyridyle, et R1 est un hydrogène ou un groupe formant un ester biolabile; sels d'addition avec un acide, notamment avec les acides de formule I, acceptables physiologiquement,

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