Piperazinyl derivatives of purines and isosteres thereof as...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/495 (2006.01) C07D 473/00 (2006.01) C07D 473/16 (2006.01) C07D 473/24 (2006.01) C07D 473/32 (2006.01) C07D 473/34 (2006.01) C07D 473/40 (2006.01) C07F 7/08 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1341043

There are disclosed certain 6-piperazino-purines and heteroaromatic derivatives thereof which have oral hypoglycemic activity and with such ability to lower blood sugar are useful in the treatment of type II diabetes and/or obesity with associated insulin resistance. Processes for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.

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