Piperidin-acetamide derivatives for the treatment of...

Details Piperidin-acetamide derivatives for the treatment of... Piperidin-acetamide derivatives for the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 211/70 (2006.01) A61K 31/41 (2006.01) A61K 31/4409 (2006.01) A61K 31/4439 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2675348

A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, wherein R1 and R2 independently are (C6 -18)aryl or (C6-18)aryl(C1-6)alkyl one or morefold substituted by (C1-6)alkyl, C(1-6)aIkoxy, halo(C1-6)alkyl, halogen or unsubstituted or substituted heterocyclyl having 5 or 6 ring members and 1 to 4 heteroatoms selected from N, O, S.

L'invention porte sur un composé de formule (I), dans laquelle les substituants sont tels qu'indiqués ci-dessus, qui s'utilise dans le traitement d'une maladie à médiation par l'action de CCR3, R1 et R2 représentant indépendamment l'aryle en C6-18 ou l'aryl en C6-18-alkyle en C1-6 une ou plusieurs fois substitués par l'alkyle en C1-6, l'alcoxy en C1-6, l'halo-alkyle en C1-6, l'halogène ou l'hétérocyclyle non substitué ou substitué ayant 5 ou 6 chaînons et 1 à 4 hétéroatomes choisis parmi N, O, S.

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