C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 413/14 (2006.01) C07D 453/02 (2006.01)
Patent
CA 2258753
The invention relates to compounds of formula (I) or a salt, solvate, or physiologically functional derivative thereof, in which X represents either CH2-CH2 or CH=CH; Y represents a group (a) or (b); R0 represents SO2Me or CONH2, and R1 represents SO2Me, to processes for their preparation, to pharmaceutical compositions containing such compounds and to their use in medicine, particularly in the treatment of thrombotic disorders.
L'invention concerne les composés de la formule (I), ou un sel, un solvate, ou un dérivé physiologiquement fonctionnel de ces derniers, où X représente CH¿2?-CH¿2? ou CH=CH; Y représente un groupe de la formule (a) ou (b) où R?0¿ représente SO¿2?Me ou CONH¿2? et R?1¿ représente SO¿2?Me. L'invention traite aussi de procédés pour leur préparation, de compositions pharmaceutiques contenant ces composés et de leur utilisation en médecine, en particulier, pour traiter les troubles thrombotiques.
Allen David George
Eldred Colin David
Judkins Brian David
Mitchell William Leonard
Glaxo Group Limited
Swabey Ogilvy Renault
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