C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/242
C07D 211/32 (2006.01) C07D 211/28 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 473/10 (2006.01)
Patent
CA 1317941
5702-256 Abstract of the Disclosure A new piperidine compound is pharmacologically effective for treatment of the arrythmia and is defined by the formula: Image in which R1 is a lower alkyl or a tolyl, R2 is hydrogen, hydroxyl, a lower alkoxy or a lower alkyl, R3 is hydrogen, a lower alkyl, a lower alkenyl, a cycloalkyl or a cycloalkylalkyl, X is -CO-, -CH2- or -CHOH-, g is an integer of 1 to 3, h is an integer of 1 to 3, Y is hydrogen, a lower alkyl, a lower alkenyl, cyano, -CH2COOR, R being hydrogen or a lower alkyl, a cycloalkyl a cycloalkylalkyl, Image 1 being 1 or 2, -A-B, A being -(CH2)n-, n being an integer of 1 to 5, a straight-chain alkylene group having 1 to 5 carbon atoms which is a divalent group derived from a straight-chain alkane having lower alkyl, phenyl or hydroxyl group(s) bonded directly to one or more carbon atoms consti- tuting said alkane by removing a hydrogen atom bonded to each of the carbon atoms placed at both ends thereof, a straight-chain alkylene group having 1 to 5 carbon atoms which is a divalent group derived from a straight-chain alkene having a double bond formed between carbon atoms adjacent to each other by removing a hydrogen atom bonded to each of the carbon atoms placed at both ends thereof, -(CH2)k-S-, k being an integer of 2 to 5, -(CH2)p- CO-, p being an integer of 1 to 4, B being cyano, -NR4R5, a heterocyclic ring or a condensed aromatic ring.
530571
Daiku Yoshiharu
Hoshiko Tomonori
Minami Norio
Miyake Kazutoshi
Nomoto Kenichi
Eisai Co. Ltd.
Smart & Biggar
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