C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/232, 260/291
C07D 211/46 (2006.01) A61K 31/445 (2006.01) C07D 211/54 (2006.01)
Patent
CA 2015949
ABSTRACT: A piperidine derivative represented by the following general formula (I): Image (I) wherein R1 and R2 are the same or different and each independently represents a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group; R3 represents a hydrogen atom or a lower alkyl group; X represents an oxygen atom or a sulfur atom; Y represents an alkylene group having 1 to 7 carbon atoms which may be optionally substituted with a lower alkyl group, or Y represents an -A-O-B- group wherein A and B are the same or different and each independently represents an alkylene group having 1 to 3 carbon atoms which may be optionally substituted with a lower alkyl group is disclosed. Also disclosed are a pharmacologically acceptable salt of a compound of formula (I), an antihistaminic and antiallergic agent comprising a compound of formula (I), a pharmaceutical composition comprising a compound of formula (I), and a method for the treatment of an allergic disease by administering a compound of formula (I). 9 1
Ito Yasuo
Kato Hideo
Koshinaka Eiichi
Nishino Hiroyuki
Ogawa Nobuo
Hokuriku Pharmaceutical Co. Ltd.
Johnson Douglas S. Q.c.
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